Variation in the pattern of synonymous and nonsynonymous difference between two fungal genomes.

doi:10.1093/molbev/msi120

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Article

Variation in the pattern of synonymous and nonsynonymous difference between two fungal genomes.

Molecular biology and evolution - 1 May 2005

Hughes Austin L, Friedman Robert

Abstract excerpt

The proportion of synonymous nucleotide differences per synonymous site (p(S)) and the proportion of nonsynonymous differences per nonsynonymous site (p(N)) were computed at 1,993,217 individual codons in 4,133 protein-coding genes between the two yeast species Saccharomyces cerevisiae and Saccharomyces paradoxus. When the modified Nei-Gojobori method was used, significantly more codons with p(N) > p(S) were...

Topics

Codon
Genetic Variation
Genome, Fungal
Models, Genetic
Mutation
Saccharomyces
Selection, Genetic

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Open in PubMed

Identifiers

PMID: 15746015
DOI: 10.1093/molbev/msi120

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