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Comparative genomics and the study of evolution by natural selection.

Molecular ecology - 1 Nov 2008

Ellegren Hans

Abstract excerpt

Genomics profoundly affects most areas of biology, including ecology and evolutionary biology. By examining genome sequences from multiple species, comparative genomics offers new insight into genome evolution and the way natural selection moulds DNA sequence evolution. Functional divergence, as manifested in the accumulation of nonsynonymous substitutions in protein-coding genes, differs among lineages in a...

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PMID: 19140982
DOI: 10.1111/j.1365-294X.2008.03954.x

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