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Article

Evidence for abundant slightly deleterious polymorphisms in bacterial populations.

Genetics - 1 Feb 2005

Hughes Austin L

Abstract excerpt

The nearly neutral theory of molecular evolution predicts that slightly deleterious mutations subject to purifying selection are widespread in natural populations, particularly those of large effective population size. To test this hypothesis, the standardized difference between pairwise nucleotide difference and number of segregation sites (corrected for number of sequences) was estimated for 149 population data...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15545641
DOI: 10.1534/genetics.104.036939
PMCID: PMC1449124

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Source receipt: pubmed, retrieved 7 Sept 2026.

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