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Article

Tuning the mechanosensitivity of a BK channel by changing the linker length.

Cell research - 1 Aug 2008

Zhao Hucheng, Sokabe Masahiro

Abstract excerpt

Some large-conductance Ca(2+) and voltage-activated K(+)(BK) channels are activated by membrane stretch. However, the mechanism of mechano-gating of the BK channels is still not well understood. Previous studies have led to the proposal that the linker-gating ring complex functions as a passive spring, transducing the force generated by intracellular Ca(2+) to the gate to open the channel. This raises the...

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Source

Identifiers

PMID: 18663377
DOI: 10.1038/cr.2008.88

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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