Article
Mechanosensitivity of STREX-lacking BKCa channels in the colonic smooth muscle of the mouse.
American journal of physiology. Gastrointestinal and liver physiology - 1 Dec 2010
Wang Wei, Huang Haixia, Hou Dongyan, Liu Ping, Wei Hua, Fu Xiaosuo, Niu Weizhen
Abstract excerpt
Stretch sensitivity of Ca²(+)-activated large-conductance K(+) channels (BK(Ca)) has been observed in a variety of cell types and considered to be a potential mechanism in mechanoelectric transduction (MET). Mechanical stress is a major stimulator for the smooth muscle in the gastrointestinal (GI) tract. However, much about the role and mechanism of MET in GI smooth muscles remains unknown. The BK(Ca) shows a...
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