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Article

Modulation of the conductance-voltage relationship of the BK(Ca) channel by shortening the cytosolic loop connecting two RCK domains.

Biophysical journal - 5 Aug 2009

Lee Ju-Ho, Kim Hyun-Ju, Kim Hae-Deun, Lee Byoung-Cheol, Chun Jang-Soo, Park Chul-Seung

Abstract excerpt

Calcium-dependent gating of large-conductance calcium-activated potassium (BK(Ca)) channels is mediated by the intracellular carboxyl terminus, which contains two domains of regulator of K(+) conductance (RCK). In mammalian BK(Ca) channels, the two RCK domains are separated by a protein segment of 101 residues that is poorly conserved in evolution and predicted to have no regular secondary structures. We...

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Identifiers

PMID: 19651031
DOI: 10.1016/j.bpj.2009.04.058
PMCID: PMC2718151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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