Article
A quantitative assay for crossover and noncrossover molecular events at individual recombination hotspots in both male and female gametes.
Genomics - 1 Oct 2008
Ng Siemon H, Parvanov Emil, Petkov Petko M, Paigen Kenneth
Abstract excerpt
Meiotic recombination is a fundamental process in all eukaryotes. Among organisms in which recombination initiates prior to synapsis, recombination preferentially occurs in short 1-to 2-kb regions, known as recombination hotspots. Among mammals, genotyping sperm DNA has provided a means of monitoring recombination events at specific hotspots in male meiosis. To complement these current techniques, we developed an...
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