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Article

A mono-allelic bivalent chromatin domain controls tissue-specific imprinting at Grb10.

The EMBO journal - 8 Oct 2008

Sanz Lionel A, Chamberlain Stormy, Sabourin Jean-Charles, Henckel Amandine, Magnuson Terry, Hugnot Jean-Philippe, Feil Robert, Arnaud Philippe

Abstract excerpt

Genomic imprinting is a developmental mechanism that mediates parent-of-origin-specific expression in a subset of genes. How the tissue specificity of imprinted gene expression is controlled remains poorly understood. As a model to address this question, we studied Grb10, a gene that displays bra...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18650936
DOI: 10.1038/emboj.2008.142
PMCID: PMC2567399

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18650936-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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