Article
Distinct physiological and behavioural functions for parental alleles of imprinted Grb10.
Nature - 27 Jan 2011
Garfield Alastair S, Cowley Michael, Smith Florentia M, Moorwood Kim, Stewart-Cox Joanne E, Gilroy Kerry, Baker Sian, Xia Jing, Dalley Jeffrey W, Hurst Laurence D, Wilkinson Lawrence S, Isles Anthony R, Ward Andrew
Abstract excerpt
Imprinted genes, defined by their preferential expression of a single parental allele, represent a subset of the mammalian genome and often have key roles in embryonic development, but also postnatal functions including energy homeostasis and behaviour. When the two parental alleles are unequally represented within a social group (when there is sex bias in dispersal and/or variance in reproductive success),...
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