Article
The evolving landscape of imprinted genes in humans and mice: Conflict among alleles, genes, tissues, and kin.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 May 2016
Wilkins Jon F, Úbeda Francisco, Van Cleve Jeremy
Abstract excerpt
Three recent genome-wide studies in mice and humans have produced the most definitive map to date of genomic imprinting (gene expression that depends on parental origin) by incorporating multiple tissue types and developmental stages. Here, we explore the results of these studies in light of the kinship theory of genomic imprinting, which predicts that imprinting evolves due to differential genetic relatedness...
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