Article
Reciprocal imprinting of human GRB10 in placental trophoblast and brain: evolutionary conservation of reversed allelic expression.
Human molecular genetics - 15 Aug 2009
Monk David, Arnaud Philippe, Frost Jennifer, Hills Frank A, Stanier Philip, Feil Robert, Moore Gudrun E
Abstract excerpt
Genomic imprinting may have evolved not only to regulate fetal growth and development, but also behaviour. The mouse Grb10 gene provides a remarkable model to explore this idea because it shows paternal expression in brain, whereas in the placenta and most other embryonic tissues, expression is f...
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