Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative and functional interrogation of parent-of-origin allelic expression biases in the brain.

eLife - 3 Jul 2015

Perez Julio D, Rubinstein Nimrod D, Fernandez Daniel E, Santoro Stephen W, Needleman Leigh A, Ho-Shing Olivia, Choi John J, Zirlinger Mariela, Chen Shau-Kwaun, Liu Jun S, Dulac Catherine

Abstract excerpt

The maternal and paternal genomes play different roles in mammalian brains as a result of genomic imprinting, an epigenetic regulation leading to differential expression of the parental alleles of some genes. Here we investigate genomic imprinting in the cerebellum using a newly developed Bayesian statistical model that provides unprecedented transcript-level resolution. We uncover 160 imprinted transcripts,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Biostatistics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cerebellum

Share to Gene Expression Profiling

Share to Genomic Imprinting

Share to Mice, Inbred C57BL

Share to Molecular Sequence Data

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 26140685
DOI: 10.7554/eLife.07860
PMCID: PMC4512258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative and functional interrogation of parent-of-origin allelic expression biases in the brain.PMID 26140685Read ↗

High-resolution analysis of parent-of-origin allelic expression in the mouse brain.Semantic proximity Read ↗

New Perspectives on Genomic Imprinting, an Essential and Multifaceted Mode of Epigenetic Control in the Developing and Adult Brain.Semantic proximity Read ↗

Critical evaluation of imprinted gene expression by RNA-Seq: a new perspective.Semantic proximity Read ↗

Genomic imprinting on the X chromosome: implications for brain and behavioral phenotypes.Semantic proximity Read ↗

Weak parent-of-origin expression bias: Is this imprinting?Semantic proximity Read ↗

Noncanonical Genomic Imprinting Effects in Offspring.Semantic proximity Read ↗

Diseases associated with genomic imprinting.Semantic proximity Read ↗

Genome-wide analysis reveals a complex pattern of genomic imprinting in mice.Semantic proximity Read ↗

Dynamic Allelic Expression in Mouse Mammary Gland Across the Adult Developmental CycleSemantic proximity Read ↗

Diverse Non-genetic, Allele-Specific Expression Effects Shape Genetic Architecture at the Cellular Level in the Mammalian Brain.Semantic proximity Read ↗

Sex-specific parent-of-origin allelic expression in the mouse brain.Semantic proximity Read ↗

Parent-of-origin-specific allelic expression in the human placenta is limited to established imprinted loci and it is stably maintained across pregnancySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.