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Article

A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression.

American journal of physiology. Cell physiology - 1 Sept 2008

Buller Carolyn L, Loberg Robert D, Fan Ming-Hui, Zhu Qihong, Park James L, Vesely Eileen, Inoki Ken, Guan Kun-Liang, Brosius Frank C

Abstract excerpt

Glucose transport is a highly regulated process and is dependent on a variety of signaling events. Glycogen synthase kinase-3 (GSK-3) has been implicated in various aspects of the regulation of glucose transport, but the mechanisms by which GSK-3 activity affects glucose uptake have not been well...

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Share to Glucose Transporter Type 1
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Share to Ribosomal Protein S6 Kinases, 70-kDa

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Source

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Identifiers

PMID: 18650261
DOI: 10.1152/ajpcell.00554.2007
PMCID: PMC2544442

Genes

TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18650261-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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