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Article

Minimum alpha chain cytoplasmic tail sequence needed to support integrin-mediated adhesion.

The Journal of biological chemistry - 5 Aug 1994

Kassner P D, Kawaguchi S, Hemler M E

Abstract excerpt

Previously, we found that deletion of the integrin alpha 4 and alpha 2 subunit cytoplasmic domains, just after the conserved GFFKR motif, causes a loss of adhesive activity mediated by VLA-4 or VLA-2, respectively (Kassner, P.D., and Hemler, M. E. (1993) J. Exp. Med. 178, 649-60; Kawaguchi, S., a...

Topics

Amino Acid Sequence
Animals
Base Sequence
Binding Sites
CHO Cells
Cations, Divalent
Cell Adhesion
Cells, Cultured
Collagen
Cricetinae
Cricetulus
Cytoplasm
Energy Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Integrins

Molecular Sequence Data

Mutation

Oligodeoxyribonucleotides

Sequence Deletion

Source

Identifiers

PMID: 8051067

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8051067-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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