Article
Twisted gastrulation promotes BMP signaling in zebrafish dorsal-ventral axial patterning.
Development (Cambridge, England) - 1 Dec 2004
Little Shawn C, Mullins Mary C
Abstract excerpt
In vertebrates and invertebrates, the bone morphogenetic protein (BMP) signaling pathway patterns cell fates along the dorsoventral (DV) axis. In vertebrates, BMP signaling specifies ventral cell fates, whereas restriction of BMP signaling by extracellular antagonists allows specification of dorsal fates. In misexpression assays, the conserved extracellular factor Twisted gastrulation (Tsg) is reported to both...
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