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Article

Recombinases and their use in gene activation, gene inactivation, and transgenesis.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008

Bischof Johannes, Basler Konrad

Abstract excerpt

The site-specific recombinase FLP is used in Drosophila to precisely manipulate the genome, in particular, to eliminate gene function by mitotic recombination and to activate transgenes in discrete populations of cells. These approaches are already part of the standard tool kit for studying gene function. The number of applications for the FLP recombinase has increased over the years and further members of the...

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PMID: 18641947
DOI: 10.1007/978-1-59745-583-1_10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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