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Article

Use of a yeast site-specific recombinase to generate embryonic mosaics in Drosophila.

Developmental genetics - 1 Jan 1992

Dang D T, Perrimon N

Abstract excerpt

An efficient method for generating embryonic mosaics using a yeast site-specific recombinase (FLP), under the control of a heat shock promoter, is described. FLP-recombinase can promote mitotic exchange between homologous chromosomes that contain FRT (FLP Recombination Target) sequences. To demonstrate the efficiency of FLP-recombinase to generate embryonic mosaics, clones of the recessive and cell autonomous...

Topics

Animals
Clone Cells
DNA Nucleotidyltransferases
Drosophila
Female
Hot Temperature
Mitosis
Mosaicism
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1292893
DOI: 10.1002/dvg.1020130507

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1292893-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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