Article
Site-specific recombination between homologous chromosomes in Drosophila.
Science (New York, N.Y.) - 17 May 1991
Golic K G
Abstract excerpt
The ability to mark a cell and its descendants genetically so that the resulting cell clone can be distinguished from neighboring cells facilitates studies in animal biology and development. A method of generating clones by inducing homologous mitotic recombination in Drosophila with a site-specific yeast recombinase is described. This method allows for frequent mosaicism after mitotic exchange is induced at...
Topics
- Animals
- Chromosome Mapping
- Chromosomes
- Crosses, Genetic
- Drosophila
- Female
- Genotype
- Male
- Mitosis
- Models, Genetic
- Mosaicism
- Recombination, Genetic
