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Article

A stochastic carcinogenesis model incorporating multiple types of genomic instability fitted to colon cancer data.

Journal of theoretical biology - 21 Sept 2008

Little Mark P, Vineis Paolo, Li Guangquan

Abstract excerpt

A generalization of the two-mutation stochastic carcinogenesis model of Moolgavkar, Venzon and Knudson and certain models constructed by Little [Little, M.P. (1995). Are two mutations sufficient to cause cancer? Some generalizations of the two-mutation model of carcinogenesis of Moolgavkar, Venzon, and Knudson, and of the multistage model of Armitage and Doll. Biometrics 51, 1278-1291] and Little and Wright...

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Identifiers

PMID: 18640693
DOI: 10.1016/j.jtbi.2008.05.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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