Article
Parameter identifiability and redundancy in a general class of stochastic carcinogenesis models.
PloS one - 31 Dec 2009
Little Mark P, Heidenreich Wolfgang F, Li Guangquan
Abstract excerpt
BACKGROUND: Heidenreich et al. (Risk Anal 1997 17 391-399) considered parameter identifiability in the context of the two-mutation cancer model and demonstrated that combinations of all but two of the model parameters are identifiable. We consider the problem of identifiability in the recently de...
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