Article
A population perspective on multistage carcinogenesis.
Princess Takamatsu symposia - 1 Jan 1991
Moolgavkar S H
Abstract excerpt
The concept of multistage carcinogenesis is one of the central dogmas of cancer research today. Recent laboratory work suggests that many specific genetic changes are associated with carcinogenesis. At the same time, there is increasing evidence that cell proliferation kinetics are important in c...
Topics
- Adenomatous Polyposis Coli
- Colonic Neoplasms
- Female
- Genes, Tumor Suppressor
- Humans
- Male
- Models, Biological
- Mutation
- Oncogenes
