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Article

Dynamics of colorectal cancer.

Seminars in cancer biology - 1 Dec 2005

Michor Franziska, Iwasa Yoh, Lengauer Christoph, Nowak Martin A

Abstract excerpt

Colorectal cancer results from an accumulation of mutations in tumor suppressor genes and oncogenes. An additional defining characteristic of colorectal cancer is its genetic instability. Two main types of genetic instability have been identified. Microsatellite instability leads to an increased point mutation rate, whereas chromosomal instability refers to an enhanced rate of accumulating gross chromosomal...

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PMID: 16055342
DOI: 10.1016/j.semcancer.2005.06.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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