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Article

Quantification of simian immunodeficiency virus cytotoxic T lymphocyte escape mutant viruses.

AIDS research and human retroviruses - 1 Aug 2008

Loh Liyen, Kent Stephen J

Abstract excerpt

Escape from cytotoxic T-lymphocyte (CTL) pressure is common in HIV-1 infection of humans and simian immunodeficiency virus (SIV) infections of macaques. CTL escape typically incurs a fitness cost as reversion back to wild-type can occur upon transmission. We utilized sequence-specific primers and DNA probes with real-time polymerase chain reaction (PCR) to sensitively and specifically track wild-type and escape...

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Share to Genes, gag
Share to Macaca nemestrina
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymerase Chain Reaction

Share to Simian Acquired Immunodeficiency Syndrome

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Share to T-Lymphocytes, Cytotoxic

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Source

Identifiers

PMID: 18620496
DOI: 10.1089/aid.2007.0309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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