Article
An "escape clock" for estimating the turnover of SIV DNA in resting CD4⁺ T cells.
PLoS pathogens - 1 Jan 2012
Reece Jeanette, Petravic Janka, Balamurali Mehala, Loh Liyen, Gooneratne Shayarana, De Rose Rob, Kent Stephen J, Davenport Miles P
Abstract excerpt
Persistence of HIV DNA presents a major barrier to the complete control of HIV infection under current therapies. Most studies suggest that cells with latently integrated HIV decay very slowly under therapy. However, it is much more difficult to study the turnover and persistence of HIV DNA during active infection. We have developed an "escape clock" approach for measuring the turnover of HIV DNA in resting CD4+...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.