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Article

Vaccine-induced T cells control reversion of AIDS virus immune escape mutants.

Journal of virology - 1 Apr 2007

Fernandez Caroline S, Smith Miranda Z, Batten C Jane, De Rose Robert, Reece Jeanette C, Rollman Erik, Venturi Vanessa, Davenport Miles P, Kent Stephen J

Abstract excerpt

Many current-generation human immunodeficiency virus (HIV) vaccines induce specific T cells to control acute viremia, but their utility following infection with escape mutant virus is unclear. We studied reversion to wild type of an escape mutant simian-HIV in major histocompatibility complex-matched vaccinated pigtail macaques. High levels of vaccine-induced CD8+ T cells strongly correlated with maintenance of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17251297
DOI: 10.1128/JVI.02193-06
PMCID: PMC1866163

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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