Article
SLC6A4 variation and citalopram response.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2009
Mrazek D A, Rush A J, Biernacka J M, O'Kane D J, Cunningham J M, Wieben E D, Schaid D J, Drews M S, Courson V L, Snyder K A, Black J L, Weinshilboum R M
Abstract excerpt
The influence of genetic variations in SLC6A4 (serotonin transporter gene) on citalopram treatment of depression using the Sequenced Treatment to Relieve Depression (STAR*D) sample was assessed. Of primary interest were three previously studied polymorphisms: 1) the VNTR variation of the second intron, 2) the indel promoter polymorphism (5HTTLPR or SERT), and 3) a single nucleotide polymorphism (SNP) rs25531....
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