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Article

Catechol O-methyltransferase pharmacogenomics and selective serotonin reuptake inhibitor response.

The pharmacogenomics journal - 1 Feb 2012

Ji Y, Biernacka J, Snyder K, Drews M, Pelleymounter L L, Colby C, Wang L, Mrazek D A, Weinshilboum R M

Abstract excerpt

We applied a systematic pharmacogenetic approach to investigate the role of genetic variation in the gene encoding catechol O-methyltransferase (COMT) in individual variation in selective serotonin reuptake inhibitor (SSRI) response among depressed patients. In all, 23 single-nucleotide polymorphisms (SNPs) in COMT were genotyped using DNA from the Sequenced Treatment Alternatives to Relieve Depression (STAR(*)D)...

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Source

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Identifiers

PMID: 20877297
DOI: 10.1038/tpj.2010.69
PMCID: PMC3113454

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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