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Article

Association of mu-opioid receptor variants and response to citalopram treatment in major depressive disorder.

The American journal of psychiatry - 1 May 2010

Garriock Holly A, Tanowitz Michael, Kraft Jeffrey B, Dang Vu C, Peters Eric J, Jenkins Greg D, Reinalda Megan S, McGrath Patrick J, von Zastrow Mark, Slager Susan L, Hamilton Steven P

Abstract excerpt

OBJECTIVE: Because previous preclinical and clinical studies have implicated the endogenous opioid system in major depression and in the neurochemical action of antidepressants, the authors examined how DNA variation in the mu-opioid receptor gene may influence population variation in response to citalopram treatment. METHOD: A total of 1,953 individuals from the Sequenced Treatment Alternatives to Relieve...

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Share to Antidepressive Agents, Second-Generation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Opioid, mu

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Source

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Identifiers

PMID: 20194481
DOI: 10.1176/appi.ajp.2009.08081167
PMCID: PMC2885766

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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