SLC6A4 polymorphisms and age of onset in late-life depression on treatment outcomes with citalopram: a Sequenced Treatment Alternatives to Relieve Depression (STAR*D) report.

doi:10.1016/j.jagp.2013.02.012

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Article

SLC6A4 polymorphisms and age of onset in late-life depression on treatment outcomes with citalopram: a Sequenced Treatment Alternatives to Relieve Depression (STAR*D) report.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Nov 2014

Shiroma Paulo R, Drews Maureen S, Geske Jennifer R, Mrazek David A

Abstract excerpt

OBJECTIVE: Age at onset of first major depressive episode (MDE) does not necessarily translate into different treatment outcomes to antidepressants in late-life depression. The influence of genetic variants may affect this relationship. DESIGN: Post hoc data set analysis of the association between variants in the promoter region (indel, rs25531) and within intron 2 (Stin2 VNTR) of the SCL6A4 gene and treatment...

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PMID: 23973251
DOI: 10.1016/j.jagp.2013.02.012
PMCID: PMC4358736

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