Article
Replication potentials of vif variant viruses generated from monkey cell-tropic HIV-1 derivative clones NL-DT5/NL-DT5R.
Microbes and infection - 1 Jan 2000
Hatcho Kazuki, Kamada Kazuya, Yamashita Tomoki, Adachi Akio, Nomaguchi Masako
Abstract excerpt
To obtain monkey-tropic viruses that are more closely related to HIV-1 than the original NL-DT5/NL-DT5R clones, we constructed six vif-chimeric and two site-specific vif-mutant viruses, and examined their growth ability. Different from NL-DT5/NL-DT5R, these viruses did not grow in monkey cells. W...
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