Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Further Investigation of Simian Immunodeficiency Virus Vif Function in Human Cells

12 Oct 2004

Abstract excerpt

Primate lentivirus Vif proteins function by suppressing the antiviral activity of the cell-encoded apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like (APOBEC) proteins APOBEC3G and APOBEC3F. It has been hypothesized that species-specific susceptibilities of APOBEC proteins to Vif proteins may help govern the transmission of primate lentiviruses to new host species. Consistent with this view and with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15479843
DOI: 10.1128/jvi.78.21.12041-12046.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Further Investigation of Simian Immunodeficiency Virus Vif Function in Human CellsPMID 15479843Read ↗

Comparative analysis of the antiretroviral activity of APOBEC3G and APOBEC3F from primates.Semantic proximity Read ↗

APOBEC3F Constitutes a Barrier to Successful Cross-Species Transmission of Simian Immunodeficiency Virus SIVsmm to Humans.Semantic proximity Read ↗

Human and Rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H Demonstrate a Conserved Capacity To Restrict Vif-Deficient HIV-1Semantic proximity Read ↗

A single amino acid difference in the host APOBEC3G protein controls the primate species specificity of HIV type 1 virion infectivity factor.Semantic proximity Read ↗

Antiretroviral Activity and Vif Sensitivity of Rhesus Macaque APOBEC3 ProteinsSemantic proximity Read ↗

A single amino acid determinant governs the species-specific sensitivity of APOBEC3G to Vif action.Semantic proximity Read ↗

Lentiviral Vif Degrades the APOBEC3Z3/APOBEC3H Protein of Its Mammalian Host and Is Capable of Cross-Species ActivitySemantic proximity Read ↗

Species-specific differences in antagonism of APOBEC3 proteins by HIV-2 and SIVsmm Vif proteinsSemantic proximity Read ↗

The host restriction factor APOBEC3G and retroviral Vif protein coevolve due to ongoing genetic conflict.Semantic proximity Read ↗

Complementation of vif-defective human immunodeficiency virus type 1 by primate, but not nonprimate, lentivirus vif genesSemantic proximity Read ↗

Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif.Semantic proximity Read ↗

Restriction of foamy viruses by APOBEC cytidine deaminases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.