Article
Damage distribution and mutation spectrum: the case of 8-methoxypsoralen plus UVA in mammalian cells.
Mutation research - 1 Aug 1991
Sage E, Bredberg A
Abstract excerpt
We determined the distribution of monoadducts and biadducts induced in the supF tRNA gene carried by the shuttle vector pZ189, after exposure to 8-methoxypsoralen (8-MOP) plus a double UVA (365 nm) irradiation. These data were compared to our previously published 8-MOP-photoinduced mutation spectrum obtained after propagation of the damaged shuttle vector in mammalian cells. One mutational hot spot in an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
