Damage distribution and mutation spectrum: the case of 8-methoxypsoralen plus UVA in mammalian cells.

doi:10.1016/0165-7992(91)90004-n

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Article

Damage distribution and mutation spectrum: the case of 8-methoxypsoralen plus UVA in mammalian cells.

Mutation research - 1 Aug 1991

Sage E, Bredberg A

Abstract excerpt

We determined the distribution of monoadducts and biadducts induced in the supF tRNA gene carried by the shuttle vector pZ189, after exposure to 8-methoxypsoralen (8-MOP) plus a double UVA (365 nm) irradiation. These data were compared to our previously published 8-MOP-photoinduced mutation spect...

Topics

Animals
Base Composition
Base Sequence
Cell Line
Chromosome Aberrations
DNA Damage
DNA Repair
Escherichia coli
Genetic Vectors
Methoxsalen
Molecular Sequence Data
Mutation
Plasmids
RNA, Transfer
Ultraviolet Rays
Vero Cells

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