Article
Mutation spectra in supF: approaches to elucidating sequence context effects.
Mutation research - 30 May 2000
Canella K A, Seidman M M
Abstract excerpt
Shuttle vectors carrying the supF suppressor tRNA gene were originally developed for mutagenesis experiments in primate and human cells. Since then, the supF gene has been used as a mutation reporter in other mammalian cells, yeast, Escherichia coli, and transgenic mice. The widespread use of the vector for studies of many DNA reactive agents has produced a large database of mutation spectra. These provide...
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