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Article

High frequency plasmid recombination mediated by 28 bp direct repeats.

Molecular biotechnology - 1 Nov 2008

Ribeiro Sofia C, Oliveira Pedro H, Prazeres Duarte M F, Monteiro Gabriel A

Abstract excerpt

The stability in Escherichia coli of a mammalian expression vector (pCIneo) and its derivative candidate DNA vaccine (pGPV-PV) is described. These multicopy pMB1-type plasmids were found to recombine in several recA E. coli strains due to the presence of two 28 bp direct repeats flanking intervening sequences of 1.6 kb (pCIneo) and 3.2 kb (pGPV-PV). In this recombination event, one of the direct repeats and the...

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PMID: 18607781
DOI: 10.1007/s12033-008-9082-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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