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Article

GCN2-dependent phosphorylation of eukaryotic translation initiation factor-2alpha in Arabidopsis.

Journal of experimental botany - 1 Jan 2008

Zhang Yuhua, Wang Yifei, Kanyuka Kostya, Parry Martin A J, Powers Stephen J, Halford Nigel G

Abstract excerpt

The yeast regulatory protein kinase, general control non-derepressible-2 (GCN2) plays a key role in general amino acid control. GCN2 phosphorylates the alpha subunit of the trimeric eukaryotic translation initiation factor-2 (eIF2), bringing about a decrease in the general rate of protein synthesis but an increase in the synthesis of GCN4, a transcription factor that promotes the expression of genes encoding...

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Identifiers

PMID: 18603615
DOI: 10.1093/jxb/ern169
PMCID: PMC2504353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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