Article
Arabidopsis eIF2alpha kinase GCN2 is essential for growth in stress conditions and is activated by wounding.
BMC plant biology - 24 Dec 2008
Lageix Sébastien, Lanet Elodie, Pouch-Pélissier Marie-Noëlle, Espagnol Marie-Claude, Robaglia Christophe, Deragon Jean-Marc, Pélissier Thierry
Abstract excerpt
BACKGROUND: Phosphorylation of eIF2alpha provides a key mechanism for down-regulating protein synthesis in response to nutrient starvation or stresses in mammalian and yeast cells. However, this process has not been well characterized in plants RESULTS: We show here that in response to amino acid and purine starvations, UV, cold shock and wounding, the Arabidopsis GCN2 kinase (AtGCN2) is activated and...
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