Article
Arabidopsis nonresponding to oxylipins locus NOXY7 encodes a yeast GCN1 homolog that mediates noncanonical translation regulation and stress adaptation.
Plant, cell & environment - 1 Jun 2018
Izquierdo Yovanny, Kulasekaran Satish, Benito Pablo, López Bran, Marcos Ruth, Cascón Tomás, Hamberg Mats, Castresana Carmen
Abstract excerpt
Stress adaptation and translational regulation was studied using noxy7 (nonresponding to oxylipins7) from a series of Arabidopsis thaliana mutants. We identified the noxy7 mutation in At1g64790, which encodes a homolog of the yeast translational regulator General Control Nonderepressible1 (GCN1) that activates the GCN2 kinase; GCN2 in turn phosphorylates the α subunit of the translation initiation factor eIF2....
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