Article
Light Activates the Translational Regulatory Kinase GCN2 via Reactive Oxygen Species Emanating from the Chloroplast.
The Plant cell - 1 Apr 2020
Lokdarshi Ansul, Guan Ju, Urquidi Camacho Ricardo A, Cho Sung Ki, Morgan Philip W, Leonard Madison, Shimono Masaki, Day Brad, von Arnim Albrecht G
Abstract excerpt
Cytosolic mRNA translation is subject to global and mRNA-specific controls. Phosphorylation of the translation initiation factor eIF2α anchors a reversible regulatory switch that represses cytosolic translation globally. The stress-responsive GCN2 kinase is the only known kinase for eIF2α serine 56 in Arabidopsis (Arabidopsis thaliana). Here, we show that conditions that generate reactive oxygen species (ROS) in...
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