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Article

Three G.C base pairs required for the efficient aminoacylation of tRNATrp by tryptophanyl-tRNA synthetase from Bacillus subtilis.

Biochemistry - 25 Jun 2002

Xu Feng, Jiang Ge, Li Wei, He Xinxia, Jin Youxin, Wang Debao

Abstract excerpt

Acceptor stem is an essential region in the recognition of tRNAs by their cognate aminoacyl-tRNA synthetase. In this study, a library containing 20 nt random region and tryptophanyl-tRNA synthetase (TrpRS) from Bacillus subtilis were used for in vitro selection to find a new structural feature in the tRNA(Trp) acceptor stem sequence that is required for B. subtilis TrpRS recognition. After three rounds of...

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PMID: 12069601
DOI: 10.1021/bi015881g

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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