Article
Aminoacylation of tRNA in the evolution of an aminoacyl-tRNA synthetase.
Proceedings of the National Academy of Sciences of the United States of America - 10 Nov 1998
Lipman R S, Hou Y M
Abstract excerpt
Aminoacyl-tRNA synthetases catalyze aminoacylation of tRNAs by joining an amino acid to its cognate tRNA. The selection of the cognate tRNA is jointly determined by separate structural domains that examine different regions of the tRNA. The cysteine-tRNA synthetase of Escherichia coli has domains that select for tRNAs containing U73, the GCA anticodon, and a specific tertiary structure at the corner of the tRNA L...
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