The presence of a D-stem but not a T-stem is essential for triggering aminoacylation upon anticodon binding in yeast methionine tRNA.

doi:10.1006/jmbi.1995.0279

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Article

The presence of a D-stem but not a T-stem is essential for triggering aminoacylation upon anticodon binding in yeast methionine tRNA.

Journal of molecular biology - 26 May 1995

Senger B, Aphasizhev R, Walter P, Fasiolo F

Abstract excerpt

Dissection of the yeast cytoplasmic initiator tRNA(Met) into two helical domains, the T psi C acceptor and anticodon minihelices, failed to show anminoacylation and binding of the acceptor minihelix by the yeast methionyl-tRNA synthetase (MetRS) even in the presence of the anticodon minihelix. In...

Topics

Acylation
Animals
Anticodon
Base Sequence
Caenorhabditis elegans
Cattle
Molecular Sequence Data
Molecular Structure
Mutation
RNA, Transfer, Met
Saccharomyces cerevisiae

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