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Article

Should thiopurine methyltransferase genotypes and phenotypes be measured before thiopurine therapy in patients with inflammatory bowel disease?

Therapeutic drug monitoring - 1 Dec 2012

Fangbin Zhang, Xiang Gao, Minhu Chen, Liang Ding, Feng Xu, Min Huang, Pinjin Hu

Abstract excerpt

BACKGROUND AND AIMS: Not all of the adverse effects to thiopurine therapy can be explained by thiopurine methyltransferase (TPMT) polymorphisms. This study was intended to evaluate the value of TPMT genotype and phenotype measurement during the first year of thiopurine therapy. METHODS: Consecutive patients with inflammatory bowel disease (IBD) who were receiving azathioprine or 6-mercaptopurine were followed up...

Read the complete abstract on PubMed

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Share to Anti-Inflammatory Agents, Non-Steroidal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23149442
DOI: 10.1097/FTD.0b013e3182731925

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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