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Article

Gene expression profiles of luteal phase fallopian tube epithelium from BRCA mutation carriers resemble high-grade serous carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2008

Tone Alicia A, Begley Heather, Sharma Monika, Murphy Joan, Rosen Barry, Brown Theodore J, Shaw Patricia A

Abstract excerpt

PURPOSE: To identify molecular alterations potentially involved in predisposition to adnexal serous carcinoma (SerCa) in the nonmalignant fallopian tube epithelium (FTE) of BRCA1/2 mutation carriers, given recent evidence implicating the distal FTE as a common source for SerCa. EXPERIMENTAL DESIGN: We obtained and compared gene expression profiles of laser capture microdissected nonmalignant distal FTE from 12...

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Share to Cystadenocarcinoma, Serous
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

Share to Genes, BRCA1

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Source

Identifiers

PMID: 18593983
DOI: 10.1158/1078-0432.CCR-07-4959

Genes

BRCA1
DAB2
SKIL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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