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Article

Differential gene expression in ovarian tumors reveals Dusp 4 and Serpina 5 as key regulators for benign behavior of serous borderline tumors.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Oct 2005

Sieben Nathalie L G, Oosting Jan, Flanagan Adrienne M, Prat Jaime, Roemen Guido M J M, Kolkman-Uljee Sandra M, van Eijk Ronald, Cornelisse Cees J, Fleuren Gert Jan, van Engeland Manon

Abstract excerpt

PURPOSE: Ovarian serous borderline tumors (SBT) are characterized by arborizing papillae lined by stratified epithelial cells, varying atypia, and absence of stromal invasion. Originally, these tumors have been classified as borderline because they behaved in a remarkably indolent manner, even with widespread tumor deposits called implants and the presence of lymph node involvement. The molecular biology of these...

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Identifiers

PMID: 16087957
DOI: 10.1200/JCO.2005.02.2541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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