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Preneoplastic Lesions Fimbria Early Diagnosis Markers Underlying Timeline Mechanisms at The Origin of Ovarian Cancer in BRAC1/2 Patients: Case Reports Based on Proteogenomic Study

2021-01-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> : BRCA 1 or 2 mutations have been known to be drivers of high-grade serous ovarian carcinomas (HGSC). As no efficient screening is currently available, a bilateral prophylactic salpingo-oophorectomy is the recommended procedure to avoid this often lethal carcinomas. However, a proportion of BRCA mutation carriers refuse to undergo this procedure due to significan...

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Literature Corpus work: f03a8fda-0785-590e-887c-e8fb3a27d233
DOI: 10.21203/rs.3.rs-152452/v1

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