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Article

Sequential molecular changes and dynamic oxidative stress in high-grade serous ovarian carcinogenesis.

Free radical research - 1 Oct 2017

Kobayashi Hiroshi, Ogawa Kenji, Kawahara Naoki, Iwai Kana, Niiro Emiko, Morioka Sachiko, Yamada Yuki

Abstract excerpt

The mechanism of high-grade serous ovarian cancer (HGSC) development remains elusive. This review outlines recent advances in the understanding of sequential molecular changes associated with the development of HGSC, as well as describes oxidative stress-induced genomic instability and carcinogenesis. This article reviews the English language literature between 2005 and 2017. Clinicopathological features analysis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28931330
DOI: 10.1080/10715762.2017.1383605

Genes

BRCA1
CCNE1
PAX2
PTEN
STMN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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