Article
Analysis of strand transfer and template switching mechanisms of DNA gap repair by homologous recombination in Escherichia coli: predominance of strand transfer.
Journal of molecular biology - 12 Sept 2008
Izhar Lior, Goldsmith Moshe, Dahan Ronny, Geacintov Nicholas, Lloyd Robert G, Livneh Zvi
Abstract excerpt
Daughter strand gaps formed upon interruption of replication at DNA lesions in Escherichia coli can be repaired by either translesion DNA synthesis or homologous recombination (HR) repair. Using a plasmid-based assay system that enables discrimination between strand transfer and template switching (information copying) modes of HR gap repair, we found that approximately 80% of strand gaps were repaired by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
