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Article

Depression and anxiety in relation to catechol-O-methyltransferase Val158Met genotype in the general population: the Nord-Trøndelag Health Study (HUNT).

BMC psychiatry - 25 Jun 2008

Baekken Petter M, Skorpen Frank, Stordal Eystein, Zwart John-Anker, Hagen Knut

Abstract excerpt

BACKGROUND: The catechol-O-methyltransferase (COMT) gene contains a functional polymorphism, Val158Met, which has been linked to anxiety and depression, but previous results are not conclusive. The aim of the present study was to examine the relationship between the Val158Met COMT gene polymorphism and anxiety and depression measured by the Hospital Anxiety and Depression Scale (HADS) in the general adult...

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Source

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Identifiers

PMID: 18578865
DOI: 10.1186/1471-244X-8-48
PMCID: PMC2453123

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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