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Article

The functional Val158Met polymorphism in catechol-O-methyltransferase (COMT) is associated with depression and motivation in men from a Swedish population-based study.

Journal of affective disorders - 1 Mar 2011

Åberg Elin, Fandiño-Losada Andrés, Sjöholm Louise K, Forsell Yvonne, Lavebratt Catharina

Abstract excerpt

BACKGROUND: Environmental risk factors together with genetic vulnerability create a complex background to develop depression. METHODS: We investigated the associations between COMT Val(158)Met and depression in a Swedish population-based sample of 405 depressed individuals (major depression diagnosis, dysthymia or mixed anxiety depression defined according to DSM-IV) and 2,151 healthy controls. We also analyzed...

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Source

Identifiers

PMID: 20828831
DOI: 10.1016/j.jad.2010.08.009

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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