Meta-Analysis of the COMT Val158Met Polymorphism in Major Depressive Disorder: Effect of Ethnicity.

doi:10.1007/s11481-016-9651-3

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Meta-Analysis of the COMT Val158Met Polymorphism in Major Depressive Disorder: Effect of Ethnicity.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology - 1 Sept 2016

Wang Maiqiu, Ma Yunlong, Yuan Wenji, Su Kunkai, Li Ming D

Abstract excerpt

The COMT (catechol-O-methyltransferase) Val158Met polymorphism (rs4680) is a potential susceptibility variant for major depressive disorder (MDD). Although many genetic studies have examined the association between MDD and this polymorphism, the results were inconclusive. In the present study, we conducted a series of meta-analyses of samples consisting of 2905 MDD cases and 2403 controls with the goal of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Catechol O-Methyltransferase

Share to Depressive Disorder, Major

Share to Ethnicity

Share to COMT gene

Share to Methionine

Share to Polymorphism, Single Nucleotide

Share to Valine

Source

Open in PubMed

Identifiers

PMID: 26803486
DOI: 10.1007/s11481-016-9651-3

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Meta-Analysis of the COMT Val158Met Polymorphism in Major Depressive Disorder: Effect of Ethnicity.PMID 26803486Read ↗

Meta-analysis of the COMT Val158Met polymorphism in major depressive disorder: the role of gender.Semantic proximity Read ↗

Association between COMT Val158Met and psychiatric disorders: A comprehensive meta-analysis.Semantic proximity Read ↗

Association of the COMT synonymous polymorphism Leu136Leu and missense variant Val158Met with mood disorders.Semantic proximity Read ↗

Catechol-O-methyltransferase val108/158met genotype, major depressive disorder and response to selective serotonin reuptake inhibitors in major depressive disorder.Semantic proximity Read ↗

The impact of catechol-O-methyltransferase SNPs and haplotypes on treatment response phenotypes in major depressive disorder: a case-control association study.Semantic proximity Read ↗

Catechol-O-methyltransferase (COMT) pharmacogenetics in the treatment response phenotypes of major depressive disorder (MDD).Semantic proximity Read ↗

The Role of a Catechol-O-Methyltransferase (COMT) Val158Met Genetic Polymorphism in Schizophrenia: A Systematic Review and Updated Meta-analysis on 32,816 Subjects.Semantic proximity Read ↗

Association study of Catechol-O-Methyltransferase (COMT) rs4680 Val158Met gene polymorphism and suicide attempt in Mexican adolescents with major depressive disorder.Semantic proximity Read ↗

Depression and the role of genes involved in dopamine metabolism and signalling.Semantic proximity Read ↗

Meta-analysis of COMT val158met in panic disorder: ethnic heterogeneity and gender specificity.Semantic proximity Read ↗

The Catechol-O-methyltransferase Val(108/158)Met Genetic Polymorphism cannot be Recommended as a Biomarker for the Prediction of Venlafaxine Efficacy in Patients Treated in Psychiatric Settings.Semantic proximity Read ↗

The role of COMT gene variants in depression: Bridging neuropsychological, behavioral and clinical phenotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.